| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2029283 | Steroids | 2011 | 8 Pages |
Abstract
⺠To analyze the effect of a replacement therapy with DHEA-S on plasma fatty acids since it has not been studied yet in humans. ⺠DHEA-S treatment produced significant changes in plasma fatty acids in post- and premenopausal obese women. ⺠DHEA-S treatment decreased total saturated fatty acids and increased n - 3 and n - 6 PUFA. ⺠D6-desaturase was significantly decreased in postmenopausal, whereas D5-desaturase was increased in premenopausal women. ⺠DHEA-S treatment modifies plasma FA composition towards a potentially better metabolic profile in obese women.
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Authors
C. Gómez-Santos, E. Larqué, E. Granero, J.J. Hernández-Morante, M. Garaulet,