Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2029486 | Steroids | 2008 | 9 Pages |
Abstract
Hydrolysis of 3-methoxy-16α-nitro-14,17-ethenoestra-1,3,5(10)-trien-17β-yl acetate under weakly basic conditions leads to formation of 3-methoxy-2′-oxopyrrolidino-[4′,5′:14β,15β]-estra-1,3,5 (10)-trien-17-one, the structure of which has been confirmed by X-ray analysis and some chemical transformations. The reactivity of 3-methoxy-16α-nitro-14,17-ethanoestra-1,3,5(10)-trien-17β-yl acetate under various conditions of basic hydrolysis has been investigated. The derived compounds have been identified by means of NMR spectroscopy and X-ray analysis.
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Authors
Alexander V. Baranovsky, Dmitry A. Bolibrukh, James R. Bull, Alexander S. Lyakhov, Vladimir A. Khripach,