| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2029558 | Steroids | 2006 | 6 Pages |
Abstract
20-Hydroxyecdysone, the arthropod moulting hormone, was biotransformed by the fungus Curvularia lunata NRRL 2178 to the rare ecdysteroid, 2-dehydro-3-epi-20-hydroxyecdysone, and the novel 3α,9α-cyclo ecdysteroid analogue, (20R,22R)-3β,14α,20,22,25-pentahydroxy-3α,9α-cyclo-5β-cholest-7-en-2,6-dione in 14 and 44% yields, respectively. Ponasterone A and pterosterone were similarly biotransformed to the corresponding 2-dehydro-3-epi- and 3α,9α-cyclo-analogues.
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Authors
Chatchawan Changtam, Oratai Sukcharoen, Boon-ek Yingyongnarongkul, Apichart Suksamrarn,