| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2030104 | Structure | 2006 | 11 Pages |
Abstract
We report a study of the structural dynamics of viral capsids, simulated on a microsecond timescale, by employing a coarse-graining molecular dynamics method. The method was calibrated against an all-atom simulation of one complete virus. Among the studied capsids, some collapsed rapidly, while others were found to be stable. Interlocking between coat proteins is found to be a key factor determining the stability of the capsids.
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Authors
Anton Arkhipov, Peter L. Freddolino, Klaus Schulten,