Article ID Journal Published Year Pages File Type
20304 Journal of Bioscience and Bioengineering 2015 4 Pages PDF
Abstract

We truncated the short arm of chromosome 3 to delete the aflatoxin biosynthesis gene homolog cluster using telomeric repeats in Aspergillus oryzae. The predicted deletion was confirmed by Southern blot analyses. This telomere-mediated chromosomal truncation method enables the development of an artificial chromosome in A. oryzae.

Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
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