| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2030820 | Structure | 2006 | 8 Pages |
Abstract
SummaryThe vacuolar ATPase integral membrane c-ring from Nephrops norvegicus occurs in paired complexes in a double membrane. Using cryo-electron microscopy and single particle image processing of 2D crystals, we have obtained a projection structure of the c-ring of N. norvegicus. The c-ring was found to be very flexible, most likely as a result of an expanded conformation of the c subunits. This structure may support a role for the vacuolar ATPase c-rings in membrane fusion.
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Authors
Daniel K. Clare, Elena V. Orlova, Malcolm A. Finbow, Michael A. Harrison, John B.C. Findlay, Helen R. Saibil,