| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 20621 | Journal of Bioscience and Bioengineering | 2013 | 4 Pages |
Abstract
The biotransformation of 14-deoxy-14-methylenetriptolide by Neurospora crassa CGMCC AS 3.1604 to produce a new hydroxylation derivative was studied. The structure of this novel compound was determined using spectral data. This biotransformation using whole cells conditioned for 4 days transformed approximately 65% (mol ratio) of the substrate into the compound (5R)-5-hydroxy-14-deoxy-14-methylenetriptolide.
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Authors
Zhouzhou Chen, Ji'an Li, Huimin Lin, Lei Shao, Jihong Qin, Xing Fan, Xiaojing Dong, Daijie Chen,