Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
20636 | Journal of Bioscience and Bioengineering | 2014 | 4 Pages |
Abstract
Human erythropoietin produced in the egg white of chimeric chicken contains N-glycan with lower amounts of terminal galactose and sialic acid; therefore, the chicken galactosyltransferase gene was introduced together with the human erythropoietin gene by a retroviral vector. We found that erythropoietin accumulated in the egg white was partially galactosylated.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Yusuke Kojima, Jun Wakita, Yujin Inayoshi, Ryosuke Suzuki, Yuki Yamada, Hidenori Kaneoka, Ken-ichi Nishijima, Shinji Iijima,