| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2091212 | Journal of Microbiological Methods | 2006 | 4 Pages |
Abstract
We compared the performance of the BacT/ALERT automated blood culture system with real-time, quantitative volatile organic compound (VOC) detection by selected ion flow tube–mass spectrometry (SIFT-MS). Blood samples from healthy donors were artificially infected with 5 or 100 CFU of organisms commonly causing bacteremia. Positive results by SIFT-MS analysis of headspace gases were recorded for 53/60 (88.3%) bottles at 8h, and 58/60 (96.6%) bottles at 24 h. We conclude that SIFT-MS is a sensitive method for the detection of microbial VOCs. Furthermore, profiles of the VOCs detected may allow simultaneous identification of infecting organisms.
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Authors
J.M. Scotter, R.A. Allardyce, V.S. Langford, A. Hill, D.R. Murdoch,