Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2093951 | Stem Cell Research | 2016 | 4 Pages |
Abstract
We established a human embryonic stem cell (hESC) line chHES-427 from the abnormal embryo carrying homozygous deletion of exon 7 of survival motor neuron gene (SMN). This cell line maintained a normal karyotype 46, XX during long-term culture. Further characteristic analysis suggested that the cells expressed the pluripotency-related markers and had the capacity to differentiate into the derivatives from the three germ layers in vitro.
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Authors
Pingyuan Xie, Hao Zhou, Xiaoying Zhou, Xiaomeng Zhao, Juan Du, Guangxiu Lu, Ge Lin, Qi Ouyang,