Article ID Journal Published Year Pages File Type
21088 Journal of Bioscience and Bioengineering 2010 4 Pages PDF
Abstract

Using yeast genetic complementation, we show here that Rhodobacter sphaeroidesl-lactate dehydrogenase can functionally replace flavocytochrome b2 in Saccharomyces cerevisiae, only when a matrix-targeting signal of flavocytochrome b2 is fused with the bacterial enzyme. The recombinant l-lactate dehydrogenase may add alternative route of mitochondrial electron transport other than flavocytochrome b2.

Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
Authors
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