Article ID Journal Published Year Pages File Type
21302 Journal of Bioscience and Bioengineering 2012 4 Pages PDF
Abstract

The gene manE, encoding a probable class I endoplasmic reticulum 1,2-α-mannosidases (ER-Man), was identified from the filamentous fungus Aspergillus oryzae due to similarity to orthologs. It removes a single mannose residue from Man9GlcNAc2, generating Man8GlcNAc2 isomer B. Disruption of manE caused drastic decreases in ER-Man activity in A. oryzae microsomes.

Related Topics
Physical Sciences and Engineering Chemical Engineering Bioengineering
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