Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
21302 | Journal of Bioscience and Bioengineering | 2012 | 4 Pages |
Abstract
The gene manE, encoding a probable class I endoplasmic reticulum 1,2-α-mannosidases (ER-Man), was identified from the filamentous fungus Aspergillus oryzae due to similarity to orthologs. It removes a single mannose residue from Man9GlcNAc2, generating Man8GlcNAc2 isomer B. Disruption of manE caused drastic decreases in ER-Man activity in A. oryzae microsomes.
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Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Takeshi Akao, Akinori Yahara, Kazutoshi Sakamoto, Osamu Yamada, Osamu Akita, Takashi Yoshida,