Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
21425 | Journal of Bioscience and Bioengineering | 2009 | 4 Pages |
Abstract
Phytochelatins (PCs) are heavy-metal-binding peptides found in some eukaryotes. This study investigates the use of plant-derived PCs for the inhibition of metal-induced protein aggregation. The results of this study show that PCs inhibit zinc-induced α-crystallin aggregation, and suggest that PCs might be useful as anti-cataract agents.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Yasuhisa Hori, Tomoaki Yoshikawa, Naoki Tsuji, Takeshi Bamba, Yoshikazu Aso, Motonori Kudou, Yoshiki Uchida, Masahiro Takagi, Kazuo Harada, Kazumasa Hirata,