| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 21993 | Journal of Bioscience and Bioengineering | 2009 | 4 Pages |
Abstract
A multilayered keratinocyte sheet overexpressing human beta defensin-3 (HBD-3) gene was prepared by the magnetic force-based tissue engineering technique. The cell sheet demonstrated significant antimicrobial activity, indicating that the therapeutic introduction of HBD-3 gene into cell sheets may provide a new gene therapy strategy for infectious diseases.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Akira Ito, Tetsuya Takahashi, Yoshinori Kawabe, Masamichi Kamihira,