| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 22488 | Journal of Bioscience and Bioengineering | 2007 | 4 Pages |
Abstract
We tested the short-term efficacy of liposome-encapsulated hemoglobin (LEH) in cultured rat hepatocytes. Supplementation with LEH (20% of the hemoglobin concentration of blood) did not lower albumin production in static culture, and completely reversed the cell death and deterioration in albumin production caused by an oxygen shortage in 2D flat-plate perfusion bioreactors.
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Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Hirosuke Naruto, Hongyun Huang, Masaki Nishikawa, Nobuhiko Kojima, Atsushi Mizuno, Katsuji Ohta, Yasuyuki Sakai,