Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2401854 | Tuberculosis | 2007 | 4 Pages |
Abstract
SummaryBeijing/W strains of Mycobacterium tuberculosis cause the vast majority of tuberculosis cases in Shanghai, China. Such highly prevalent strains are considered as hypervirulent and are often associated with multi-drug resistance, treatment failure and HIV status. We present a reliable and fast detection method to identify these Beijing/W strains, which can be applied to screening large numbers of samples at low cost. Using this Deletion-Targeted Multiplex PCR (DTM-PCR) method for detecting these strains, we obtained 100% sensitivity and specificity.
Keywords
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Applied Microbiology and Biotechnology
Authors
Jing Chen, Anthony G. Tsolaki, Xin Shen, Xi Jiang, Jian Mei, Qian Gao,