Moxifloxacin

Generic and additional names: Moxifloxacin HydrochlorideCAS name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochlorideCAS registry #: 186826-86-8Molecular formula: C21H24FN3O4·HClMolecular weight: 437.89Intellectual property rights: BayerBrand names: Actimax (Sankyo); Actira (Bayer); Avelox (Bayer); Octegra (Bayer); Proflox (Esteve); Vigamox(Alcon)Derivatives: Moxifloxacin is a quinolone/fluoroquinolone antibiotic related to ciprofloxacin, enoxacin, fleroxacin, gatifloxacin, gemifloxacin, grepafloxacin, levofloxacin, lomefloxacin, norfloxacin, ofloxacin, pefloxacin, prulifloxacin, rufloxacin, sparfloxacin, temafloxacin, trovafloxacin, sitafloxacinSolubility: Soluble in waterPolarity: Log P 2.033 [DrugBank]Melting point: 238–242ºC [DrugBank]Formulation and optimal human dosage: Avelox tablets: containing moxifloxacin hydrochloride (equivalent to 400 mg moxifloxacin).Avelox i.v.: 250 ml latex-free flexibags as a sterile, preservative-free, 0.8% sodium chloride aqueous solution of moxifloxacin hydrochloride (containing 400 mg moxifloxacin).400 mg daily doseFigure optionsDownload full-size imageDownload high-quality image (19 K)Download as PowerPoint slide