Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
240403 | Procedia Chemistry | 2015 | 7 Pages |
Abstract
The anti-inflammatory effect caused by VNN infection in the grouper fish using pigment-protein fraction of N.oculata has studied. Methods were to explore the pigment-protein fraction of N.oculata, in vivo test, and measurement of anti-inflammatory response using dot blott and immunohistochemistry technique. Results indicate that pigment-protein fraction of N. oculata was able to suppress grouper tissue inflammation when VNN infection was occurring. Inflammation sign was reduced by administration of pigment-protein fraction. This reaction was reinforced by raising of expression of TNFα and IL-6, which means that TNFα and IL-6 acts as an anti-inflammatory in fish tissue.
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