Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
24460 | Journal of Biotechnology | 2010 | 4 Pages |
Abstract
Human embryonic stem cells (hESCs) have numerous potential biomedical applications owing to their unique abilities for self-renewal and pluripotency. Successful clinical application of hESCs and derivatives necessitates the culture of these cells in a fully defined environment. We have developed a novel peptide-based surface that uses a high-affinity cyclic RGD peptide for culture of hESCs under chemically defined conditions.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Bioengineering
Authors
Poornima Kolhar, Venkata Ramana Kotamraju, Sherry T. Hikita, Dennis O. Clegg, Erkki Ruoslahti,