| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 24478 | Journal of Biotechnology | 2010 | 4 Pages |
Abstract
Nitroalkanes underwent fast additions to a variety of structurally diverse aldehydes under the catalysis of d-aminoacylase in DMSO. The influences of reaction conditions including solvents, temperature, enzyme concentration and molar ratio of substrates were systematically investigated. Seventeen products were obtained in short time with moderate to high yields. It is the first report on hydrolase-catalyzed fast Henry reaction in organic solvent.
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Authors
Jun-Liang Wang, Xia Li, Hong-Yan Xie, Bo-Kai Liu, Xian-Fu Lin,