Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
24604 | Journal of Biotechnology | 2009 | 12 Pages |
Abstract
Cannabis sativa L. plants produce a diverse array of secondary metabolites. Cannabis cell cultures were treated with biotic and abiotic elicitors to evaluate their effect on secondary metabolism. Metabolic profiles analysed by 1H NMR spectroscopy and principal component analysis (PCA) showed variations in some of the metabolite pools. However, no cannabinoids were found in either control or elicited cannabis cell cultures. Tetrahydrocannabinolic acid (THCA) synthase gene expression was monitored during a time course. Results suggest that other components in the signaling pathway can be controlling the cannabinoid pathway.
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Authors
Isvett Josefina Flores-Sanchez, Jaroslav Peč, Junni Fei, Young Hae Choi, Jaroslav Dušek, Robert Verpoorte,