Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2473789 | Procedia in Vaccinology | 2012 | 6 Pages |
Abstract
A retrospective cohort study was conducted in 2631 Colombian children <2 yrs to evaluate pneumococcal vaccine effectiveness. Association between vaccination and disease was evaluated using Cox proportional hazards models. Vaccinated children had a significant reduction in hospitalization risk for all outcomes (HR 0,59 CI 95% 0,42 - 0,85) and for pneumonia the reduction was slightly higher (HR 0,53 CI 95% 0,32 - 0,89). Our results show an important risk reduction in clinical syndromes potentially associated to pneumococcus in vaccinated children confirming the benefits of using conjugate vaccines in a medium income developing country.
Related Topics
Life Sciences
Immunology and Microbiology
Immunology and Microbiology (General)