Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2478692 | Bulletin of Faculty of Pharmacy, Cairo University | 2013 | 5 Pages |
Abstract
A bioactivity-guided investigation of the ethanolic extract (70%) of the stem bark of Pterocarpus dalbergioides Roxb. ex DC revealed that the butanol fraction possessed potent antihyperglycemic and anti-inflammatory activities at a dose of 100 mg/kg b.wt. compared to metformin (150 mg/kg b.wt.) and indomethacin (20 mg/kg b.wt.) respectively. Two phenolic acids viz: gentisic (1) and gallic (3) acids and isoflavone genistin (2) were isolated for the first time from the studied plant adopting a bioactivity-guided fractionation. Identification of the isolated compounds was achieved using physical, chemical and spectroscopic data.
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Authors
Camilia Michel, Moshera El-sherei, Wafaa Islam, Amani Sleem, Shaimaa Ahmed,