| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2480977 | European Journal of Pharmaceutical Sciences | 2011 | 6 Pages |
Abstract
The solubilisation of two natural compounds, griseofulvin and rutin, in micellar solutions of mixtures of gemini (N,N′-didecyl-N,N,N′,N′-tetramethylethane-1,2-diyldiammonium dibromide) and heterogemini (decyl 2-[decyl(dimethyl)ammonio]ethylphosphate) surfactants has been studied. The highest solubilisation capacities were found for mixtures with a molar fraction of heterogemini surfactant equal or greater than the molar fraction of gemini surfactant. The relationship between synergism in surface properties of mixtures of surfactants and their solubilisation properties was also investigated.
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Authors
Miloš Lukáč, Ivan Prokipčák, Ivan Lacko, Ferdinand Devínsky,