Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2481283 | European Journal of Pharmaceutical Sciences | 2011 | 6 Pages |
Abstract
The present study demonstrates that the difference between the activity and the antigen profiles of rFVIIa and NN1731 in Beagle dogs is the result of complex formation with AT which constitutes a major pathway for the clearance of rFVIIa activity.
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Authors
Henrik Agersø, Niels Rode Kristensen, Henrik Ãstergaard, Ditte Maria Karpf, Mette Brunsgaard Hermit, Hermann Pelzer, Lars Christian Petersen, Mirella Ezban,