Article ID Journal Published Year Pages File Type
2483757 Journal of Drug Delivery Science and Technology 2007 5 Pages PDF
Abstract

Presbyopia is an age-related condition that begins to develop in humans around the age of forty, resulting in anatomical and physiological changes in the choroids, ciliary body, vitreous, lens capsule, and lens fibers. A suitable biomaterial is needed for the implantation of intraocular lenses (IOL) that could be used to treat the symptoms of presbyopia in people everywhere. In this paper, the characteristics of silicone polymer, polyether, poly acrylic derivatives, polyalcohol, poly(vinyl pyrrolidone) (PVP), and poly(acryl amide) hydrogels were explained, and then their biocompatibilities were compared. These types of hydrogel materials have several advantages over the current fixed-focus IOL including restoration of accommodation, minimal corneascleral trauma, improved physiological position of the IOL, and possible use in the surgical correction of cataracts.

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery