| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2483877 | Journal of Drug Delivery Science and Technology | 2006 | 4 Pages |
Abstract
A small library of α-cyclodextrin aldonamide (CDA) conjugates has been synthesized and their glucose sensing behavior examined. The partially substituted aldonamides of α-cyclodextrin were found to recognize glucose, but were unable to form the hydrogel. However, the solution of hexaaldonamides of α-cyclodextrin transformed into a hydrogel upon complexation with glucose. SEM studies revealed the presence of fibrous, intertwined, reticulate networks in the hydrogels. This type of glucose-sensitive hydrogel may be useful in developing glucose-sensors and glucose-sensitive drug delivery systems.
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