Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2485019 | Journal of Pharmaceutical Sciences | 2013 | 7 Pages |
Abstract
In this paper, we present an investigation of the polymorphism of griseofulvin. In addition to the only reported crystalline form (form I), two new polymorphic forms (II and III) have been identified and characterized by differential scanning calorimetry and powder X-ray diffraction. Reasons why these two polymorphs were isolated during the present study, but not detected during the numerous previous studies on this drug, are also discussed.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Aurelien Mahieu, Jean-francois Willart, Emeline Dudognon, Mark D. Eddleston, William Jones, Florence Danède, Marc Descamps,