Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2485884 | Journal of Pharmaceutical Sciences | 2007 | 8 Pages |
Abstract
Although cefadroxil does not exhibit the phenomenon of photoluminescence when dissolved in a fluid medium, the compound has been found to exhibit fluorescence in its solidâstate monohydrate crystal form. The monohydrate was found to exhibit complicated photoluminescence, where two different sets of emission spectra could be obtained upon irradiation with an appropriate excitation wavelength. One of these photophysical systems became strongly suppressed when the monohydrate was halfâdehydrated, and only one of the photophysical systems could be observed in this hemihydrate. In the fully dehydrated state, both photophysical pathways became almost totally suppressed, so that the nonsolvated cefadroxil became effectively nonfluorescentand the American Pharmacists Association J Pharm Sci 96: 2757-2764, 2007
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
Authors
Harry G. Brittain,