| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2486518 | Journal of Pharmaceutical Sciences | 2005 | 4 Pages |
Abstract
Iontophoretic transdermal delivery of sumatriptan was investigated in vitro. Among the conditions tested, 0.25 mA/cm2 and low ionic strength (NaCl 25 mM) was the best experimental condition to increase its transport across the skin. The flux increased 385-fold respective to passive diffusion, thus resulting in a transdermal flux of sumatriptan of 1273 ± 83 nmol/cm2 h. © 2005 Wiley-Liss, Inc. and the American Pharmacists Association
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Authors
A. FemenÃa-Font, C. Balaguer-Fernández, V. Merino, A. López-Castellano,