Article ID Journal Published Year Pages File Type
2487657 Journal of Pharmaceutical Sciences 2007 8 Pages PDF
Abstract
Progesterone rapidly dissolves in an aqueous solution containing hydroxypropyl‐β‐cyclodextrin (HPBCD) at 1:2 molar ratio, forming a soluble inclusion complex. After filtration and freeze‐drying of the final solution, the final powder was examined by SEM, DSC, TGA, XRD, Raman, and FTIR spectroscopy. Experimental results confirm that an inclusion complex exists in the solid state and possible structure of the complex is briefly discussed. © 2007 Wiley‐Liss, Inc. and the American Pharmacists Association J Pharm Sci 96: 1729-1736, 2007
Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Drug Discovery
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