Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2487677 | Journal of Pharmaceutical Sciences | 2007 | 6 Pages |
Abstract
ABSTRACTWe have extended the established physical stability treatment for hydrates/solvates to co-crystals with solid co-crystal formers. Based on the proposed treatment, a suspension/slurry screening technique is developed and tested in sixteen pharmaceutical co-crystal systems with success. The theoretical treatment and the practical screening technique should benefit the researchers in the field of co-crystallization in improving the screening efficiency. © 2007 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 96: 990–995, 2007
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Authors
Geoff G.Z. Zhang, Rodger F. Henry, Thomas B. Borchardt, Xiaochun Lou,