Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2498402 | Asian Journal of Pharmaceutical Sciences | 2016 | 8 Pages |
Abstract
The aim of the present study was to develop layered double hydroxide (LDH) nanoparticles coated with PEGylated phospholipid membrane. By comparing the size distribution and zeta potential, the weight ratio of LDH to lipid materials which constitute the outside membrane was identified as 2:1. Transmission electron microscopy photographs confirmed the core-shell structure of PEGylated phospholipid membrane coated LDH (PEG-PLDH) nanoparticles, and cell cytotoxicity assay showed their good cell viability on Hela and BALB/C-3T3 cells over the concentration range from 0.5 to 50 μg/mL.
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
Mina Yan, Zhaoguo Zhang, Shengmiao Cui, Xuefei Zhang, Weijing Chu, Ming Lei, Ke Zeng, Yunhui Liao, Yihui Deng, Chunshun Zhao,