Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2500722 | Future Journal of Pharmaceutical Sciences | 2016 | 11 Pages |
Abstract
Quinazoline derivatives are fused heterocyclic ring systems which have been explored for their inhibitory activity towards various protein kinase enzymes and their role as anticancer agents. The present review to represent the most recent synthetic strategies and medicinal aspects including structure activity relationships of substituted quinazolines as EGFR inhibitors reported to date.
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Authors
Rania S.M. Ismail, Nasser S.M. Ismail, Sahar Abuserii, Dalal A. Abou El Ella,