| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2500849 | International Journal of Pharmaceutics | 2016 | 4 Pages |
Abstract
Aim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate–plate rheometry. Microrheology was investigated using optical tweezers. Our data revealed significant differences both in macro- and micro-rheological properties between respiratory and intestinal mucus.
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Authors
Harish Bokkasam, Matthias Ernst, Marco Guenther, Christian Wagner, Ulrich F. Schaefer, Claus-Michael Lehr,