Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2500895 | International Journal of Pharmaceutics | 2016 | 4 Pages |
Abstract
The in vitro efficacy of poloxamer 407-based formulations with antifungal ciclopirox olamine has been analysed in an infected nail plate model. As artificial nail plates, keratin films made of human hair keratin and slices from bovine hooves have been utilised. Several poloxamer 407-based formulations with 1 % active ingredient indicated complete growth inhibition of the dermatophyte fungus Trichophyton rubrum after 6 days of incubation.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (222 K)Download as PowerPoint slide
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
Anja Täuber, Christel C. Müller-Goymann,