Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2501038 | International Journal of Pharmaceutics | 2016 | 5 Pages |
Abstract
The aim of the study is to check if the information about drug/liposome interactions provided by Surface Plasmon Resonance (SPR) is comparable with that provided by potentiometry in which liposomes are not immobilized on a solid support. To reach our aim we apply QSPR and BR analysis to data extracted from the literature and carefully inspected for their reliability. Results show that log KD (SPR) is governed by a different balance of intermolecular interactions than log Dlip (potentiometry).
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
Giuseppe Ermondi, Giulia Caron,