| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2501568 | International Journal of Pharmaceutics | 2015 | 4 Pages |
Abstract
Phenylboronic acid-rich nanoparticles (PBNPs) were designed as a novel mucoadhesive vaginal drug delivery system. PBNPs effectively adsorbed mucin in vitro and could be easily loaded with the model drug interferon (IFN). Drug release from PBNPs was controlled by the presence of mucin. Neither obvious cytotoxicity nor vaginal histological changes in mice caused by PBNPs or IFN-loaded PBNPs were observed.
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Authors
Chunyan Li, Zheshuo Liu, Xueying Yan, Weiyue Lu, Yu Liu,