Article ID Journal Published Year Pages File Type
2503250 International Journal of Pharmaceutics 2011 14 Pages PDF
Abstract

In this article, the use of mid-IR in pharmaceutical settings is reviewed. An overview of mid-IR instrumentation and sampling techniques is provided. Subsequently, different pharmaceutical applications of the technique are described, including structure elucidation and identification, characterization of crystalline (polymorphs, hydrates, salts and co-crystals) and amorphous forms, as well as quantitative and remote sensing applications. Finally, an overview of current trends in FTIR-based imaging applications is provided, with special attention paid to currently emerging FTIR–AFM coupled techniques which have high spatial resolution.

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Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science
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