Article ID Journal Published Year Pages File Type
2503731 International Journal of Pharmaceutics 2011 6 Pages PDF
Abstract

Mucoadhesive properties of tamarind seed polysaccharide (TSP) and larch arabinogalactan (AG), which are developed for ophthalmic applications, were investigated by NMR spectroscopy. Polysaccharide to mucin affinities were compared by using ketotifen fumarate as low molecular weight interaction probe. Proton selective relaxation rate measurements revealed enhanced affinity of TSP to mucin with respect to AG.

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmaceutical Science
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A nuclear magnetic resonance approach to the comparison of mucoadhesive properties of polysaccharides for ophthalmic uses
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