| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2504702 | International Journal of Pharmaceutics | 2009 | 4 Pages |
Abstract
The solubilisation of two poorly soluble flavonoids, quercetin and rutin, in micellar solutions of mixtures of a block copolymer of ethylene oxide and styrene oxide (E137S18E137) with one of ethylene oxide and propylene oxide (E62P39E62) has been studied at 25 and 37 °C. Solubilisation capacities were higher than those for the model poorly water-soluble drug griseofulvin and comparable with published values for the solubilisation of rutin by β-cyclodextrin.
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
Maria Elenir N.P. Ribeiro, Ícaro G.P. Vieira, Igor Marques Cavalcante, Nágila M.P.S. Ricardo, David Attwood, Stephen G. Yeates, Colin Booth,