Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2505871 | International Journal of Pharmaceutics | 2007 | 5 Pages |
Abstract
This paper describes the effect on Sun Protection Factor (SPF) of the combination of inorganic and organic filters in sunscreen products as determined by an in vitro method. O/W emulsions containing inorganic filters, such as titanium dioxide and zinc oxide, combined with 18 EU-authorized UV-B organic filters were tested. SPF measurements were carried out using a spectrophotometer equipped with an integrating sphere.This study observed a synergic effect when titanium dioxide was combined with either anisotriazine or octyldimethylPABA. The combination of zinc oxide with 11 UV-B organic filters also exhibited a similar synergy; however, the measured SPF was systematically lower than the protection factor achieved with titanium dioxide.
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Authors
S. El-Boury, C. Couteau, L. Boulande, E. Paparis, L.J.M. Coiffard,