| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2506563 | International Journal of Pharmaceutics | 2006 | 5 Pages |
Abstract
Layered double hydroxides (LDHs) were investigated as cordycepin delivery nanocarriers for the first time in this study. Negatively charged biomolecule-cordycepin was intercalated in the gallery spaces of [Mg–Al–NO3] as the charge-compensating species, which was confirmed by the results of XRD, FT-IR, TEM, CZE and electrophoretic mobility. Cell experiment suggested that the new bio-LDH nanohybrid could prevent cordycepin decomposition by adenosine deaminase. This new formulation could possibly be used as a novel form cordycepin intravenous injection.
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Authors
Qin Zheng Yang, Jing Yang, Chang Kai Zhang,