| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2507754 | Journal of Pharmaceutical Analysis | 2015 | 5 Pages |
Abstract
Cancer is a communal health hazard worldwide. The present investigation attempts to evaluate antimicrobial and anticancer potential of kosinostatin on mammary carcinoma cell line (MCF-7). The anticancer and antiproliferative activities of kosinostatin were analyzed on MCF cell line by MTT assay and cytotoxicity assays like lactate dehydrogenase (LDH) and glutathione (GSH). The secondary metabolite kosinostatin exhibited its apoptotic nature by expressing p53 protein. Collectively, the results acquired from this study promise that kosinostatin shows the potent anticancer activity.
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Authors
Vinayagam Rambabu, Subramaniyan Suba, Suburamaniyan Vijayakumar,