| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2507895 | Journal of Pharmaceutical Analysis | 2014 | 7 Pages |
Abstract
The quantitative estimation of amikacin (AMK) in AMK sulfate injection samples is reported using FTIR-derivative spectrometric method in a continuous flow system. Fourier transform of mid-IR spectra were recorded without any sample pretreatment. A good linear calibration (r>0.999, %RSD<2.0) in the range of 7.7–77.0 mg/mL was found. The results showed a good correlation with the manufacturer's and overall they all fell within acceptable limits of most pharmacopoeial monographs on AMK sulfate.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slide
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmaceutical Science
Authors
José F. Ovalles, Máximo Gallignani, María R. Brunetto, Rebeca A. Rondón, Carlos Ayala,