| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2522632 | Biochemical Pharmacology | 2006 | 6 Pages |
Abstract
3H-digoxigenin is metabolized by rat liver homogenates to 3H-3-epidigoxigenin and 3H-3-dehydrodigoxigenin. Maximum conversion occurs after approximately 80 min of incubation. The amount of each metabolite which accumulates depends on the amount of NADP+ added to the incubation mixture. No formation of more polar metabolites was observed, indicating that a microsomal hydroxylating system may not be operative in the metabolism of digoxigenin.
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