Article ID Journal Published Year Pages File Type
2522633 Biochemical Pharmacology 2012 6 Pages PDF
Abstract

Various 5-substituted indoles are shown to inhibit effectively both the enzymatic and autoxidation of dopamine. The inhibition of the enzymatic oxidation is suggested by kinetic studies to be non-competitive. 5-Hydroxyindoles are also shown to inhibit the enzymatic oxidation of 3,4-dihydroxyphenylalanine.

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