Hepatoprotective triterpenes from the gum resin of Boswellia carterii

Ten tirucallane-type triterpenes named boscartene A–J and a nor-tetracyclic triterpene boscartene K, together with ten known compounds were isolated from the gum resin of Boswellia carterii Birdw. Their structures and absolute configurations were elucidated by extensive spectroscopic analysis. In vitro assay, some of these compounds (10 μM) showed moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage.

Graphical abstractTwenty-one triterpenes were isolated from the gum resin of B. carterii Birdw. Their structures and absolute configurations were elucidated by extensive spectroscopic analysis. Some of these compounds showed moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage.Figure optionsDownload full-size imageDownload high-quality image (163 K)Download as PowerPoint slide