Cyanogenetic glycosides and simple glycosides from the linseed meal

Three new cyanogenetic triglycosides linustatins A–C (1–3), and two new simple glycosides linustatins D and E (4 and 5) were isolated from the 70% ethanol extract of flaxseed meal (Linum usitatissimum L.). Their structures were elucidated on the basis of spectroscopic analysis and chemical evidence. All of the isolates showed moderate activities against aldose reductase and weak activities against α-glucosidase, DPP-IV, and FBPase at the same concentrations as the positive control drugs.

Graphical abstractThree new cyanogenetic triglycosides (1–3), and two simple glycosides (4 and 5) were isolated from the extract of flaxseed meal. Their structures were elucidated based on the spectroscopic analysis and chemical evidence. All of the isolates showed moderate activities against aldose reductase and weak activities against α-glucosidase, DPP-IV, and FBPase at the same concentrations as the positive control drugs.Figure optionsDownload full-size imageDownload high-quality image (422 K)Download as PowerPoint slide