Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538206 | Fitoterapia | 2015 | 7 Pages |
Abstract
Nine new sesquiterpenes (1–9), together with seventeen known ones (10–26), were isolated from Chinese eaglewood. Their structures were established by extensive spectroscopic analysis, and the absolute configuration of 6 was determined by the modified Mosher's method. Compounds 7, 10, 14, 15, and 21 exhibited significant inhibition of nitric oxide production in lipopolysaccharide-stimulated BV-2 microglial cells with IC50 values in the range 7.1–53.8 μM.
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Authors
Hui-Xia Huo, Zhi-Xiang Zhu, Dao-Ran Pang, Yue-Ting Li, Zheng Huang, She-Po Shi, Jiao Zheng, Qian Zhang, Yun-Fang Zhao, Peng-Fei Tu, Jun Li,